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(Diagram: Caseous necrosis in a tuberculous lymph node, showing the typical amorphous, granular, eosinophilic, necrotic center surrounded by granulomatous inflammation).
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Necrosis Caseous necrosis is found characteristically in tuberculosis. It is a form of coagulative necrosis, in that no liquefaction has occurred, but microscopically the affected tissue appears completely structureless, under the microscope and exhibits a greater than usual affinity for acidic dyes such as eosin.
It owes its name (caseous=cheese-like) to its macroscopic appearance, large areas of caseous necrosis bearing some resemblance to white, crumbly goat cheese. On chemical analysis, large amounts of lipid are found to be present in these necrotic areas in addition to the coagulated protein.
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