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(Diagram: Caseous necrosis in a tuberculous
lymph node, showing the typical amorphous, granular, eosinophilic,
necrotic center surrounded by granulomatous inflammation).
Visit:
Necrosis
;
Tuberculosis
;
Granulomatous Reaction Pattern of the Skin
;
Lupus Vulgaris
.
Caseous
necrosis is found characteristically in
tuberculosis.
It is a form of
coagulative necrosis, in that no liquefaction has occurred, but
microscopically the affected tissue appears completely
structureless,
under the microscope and exhibits a greater than usual
affinity for acidic dyes such as eosin.
It owes its
name (caseous=cheese-like)
to its macroscopic appearance, large areas of caseous necrosis bearing
some resemblance to white, crumbly goat cheese.
On chemical
analysis, large amounts of lipid are found to be present in these
necrotic areas in addition to the coagulated protein.

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