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(Diagram: Fibrinoid necrosis in a medium-sized
artery. The muscular media contains sharply demarcated, homogeneous,
deeply eosinophilic areas of necrosis).
Visit:
Necrosis
There is an
alteration of blood vessels known as
fibrinoid
necrosis.
In this case,
the proximity of the blood allows insudation and accumulation of plasma
proteins that cause the injured vessels to stain intensely eosinophilic,
hence the name fibrinoid necrosis.
The term is
something of a misnomer, however, because the eosinophilia of the
accumulated plasma proteins obscures the underlying alterations in the
blood vessel, making it difficult to determine whether there is truly
any necrosis of the vascular wall.

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