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Pulmonary Pathology Online Anatomy and Histology of the Normal Lung and Airways Examination of pulmonary and pleural biopsies Useful chromatic and immunostains in pulmonary pathology |
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Hematin is a brown-black pigment derived from hemoglobin. Although its precise composition has not yet been determined, it is known to contain heme iron in the ferric form. It is formed by the oxidation of heme from the ferrous Fe(II) to the ferric Fe(III) state. The pigment is associated most commonly with a severe hemolytic crisis after transfusion of incompatible blood or chronic parasitization of red blood cells by malarial protozoa. It is usually found in the cytoplasm of reticuloendothelial cells. Acid hematin is a birefringent pigment, different from hemosiderin (refractile but not birefringent). Formalin pigment and malarial pigment are acid hematin which is not stained by the Prussian blue reaction, unlike hemosiderin which stains positively.
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Acute Respiratory Distress Syndrome Neonatal Respiratory Distress Syndrome Chronic Obstructive Pulmonary Disease Emphysema |