(Diagram: Liquefaction necrosis in the epidermis and
dermis in an abscess of the skin. The abscess cavity is filled with
In liquefaction necrosis the dominant
factor is the effect of hydrolytic lysosomal enzymes.
The end result is a local accumulation of
protein-rich, semifluid material.
It is not particularly common as a
primary event except in the brain.
However, if necrotic tissue becomes
secondarily infected by pus-forming organisms, liquefaction commonly