Pathology Photo of the Day -

Blue Rubber or Beans -

Blue Rubber Bleb Nevus Syndrome (Bean's Syndrome ; BRBNS )

Dr Sampurna Roy MD                      July 2015    


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Blue Rubber Bleb Nevus Syndrome was first recognized by Gascoyen in 1860. Almost one hundred years later Bean further described these lesions and coined the term BRBNS also known as Bean's Syndrome.

Blue Rubber Bleb Nevus Syndrome ( BRBNS) is a rare disorder characterized by multiple cutaneous venous malformations in the skin and gastrointestinal tract associated with intestinal hemorrhage and iron deficiency anemia.

Other organs may also be involved, such as the central nervous system, liver, and muscles. BRBNS has a potential for serious or fatal bleeding.

The characteristic cutaneous lesions consist of deep-blue, soft, rubbery blebs, which are easily compressible.

The syndrome may also present with severe complications such as rupture, intestinal torsion, and intussusception, and can even cause death.

 

Further reading:

The blue rubber bleb nevus syndrome or Bean's syndrome. A rare cause of digestive hemorrhage.

"Blue rubber bleb nevus syndrome"--or Bean's syndrome.

The "blue rubber bleb nevus" (Bean's syndrome): uncommon cause of gastrointestinal bleeding.

Blue rubber bleb nevus syndrome: a case report and literature review.

Blue rubber bleb nevus syndrome: a case report and literature review.

Blue rubber bleb nevus syndrome: a clinical spectrum with correlation between cutaneous and gastrointestinal manifestations.

Blue rubber bleb nevus syndrome: gastrointestinal involvement and its endoscopic presentation.

Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation.

Blue rubber bleb nevus syndrome: case report and literature review.

Blue rubber bleb nevus syndrome.

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Dr  Sampurna Roy  MD

Consultant Histopathologist (Kolkata - India)

 

 

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