|Pathology Photo of the Day -
Blueberry Muffin is not for your Baby.
Blueberry Muffin Syndrome -
Dr Sampurna Roy MD May 2016
Blueberry Muffin Baby
is a rare neonatal cutaneous syndrome characterized by purpuric
of extramedullary hematopoiesis.
The blueberry muffin morphology presents as non-blanching, violaceous, magenta-colored macules, papules, nodules and plaque. These are usually 2 to 8mm in diameter.
The lesions are usually generalized but more commonly present on the trunk, head, and neck.
Many causes are known like congenital infections, vascular lesions, malignancy, systemic diseases and hematologic disorders.
- Infectious Diseases - (Infectious Disease Online)
Eruption may be associated with Cytomegalovirus, Rubella, Toxoplasmosis, Herpes virus, Parvovirus, Coxackievirus and Epstein-Barr virus and Syphilis.
Spherocytes in Hereditary Spherocytosis
- Hematologic disorder - Hereditary Spherocytosis, alloimmunization, fetomaternal transfusion, ABO blood type incompatibility, Rh incompatibility, Twin-to-twin-transfusion.
- Vascular Lesions - Multiple Hemangiomas and Glomangiomas, Blue rubber bleb nevus syndrome
- Neoplastic Lesions - Congenital leukemia, Neuroblastoma, Congenital rhabdomyosarcome, Hemangiopericytomas, /myofibromatosis.
Langerhans cell histiocytosis
- Systemic Lesions - Langerhans cell histiocytosis and Lupus.
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